No. I never do. But loctite is required or oil will leak out of the engine, making the new rear main seal you installed useless. It is more for sealing the threads than locking. Unless you have the M60 the holes on the rear flange are not through holes so no oil can come out. BMW calls for oiling the flywheel bolts on the M60 rather than loctiting them.

Sorry. I am still asleep talking about the wrong bolts. But my answer is still no.