Jeff,
The skyway is interstate 90. I urge you to avoid it. Apparently you are coming from the east, use 80/94.
The route seems to be in debate from the east. There is construction on both routes. The skyway/Dan Ryan has lane closures in the late eve. and wee hours,sometimes one lane only open. The 80/94 route has become notorious because of a long reconstruction project. This is nearly complete.
I have had no major delays there recently nor have some friends who travel the route regularly.
If you refer to an old post of mine I suggested a route that I frequently use.
Either way you choose enjoy your trip and my city.