Can't speak for the M52 motor, but the M54 in Lori's 525 is VERY picky about plugs. I tried a set of the Bosch platinum plugs in it at 55k miles. There were 2 plugs listed on the ETK, despite what others said about sticking with what it came with, I went with the Bosch. Mistake...
Well, 20k miles later and the Bosch's were throwing misfire codes and the car was running rough. I ordered up a set of the NGK's that were taken out of the car and she's all happy again. The electrode on the NGK's was much bigger than the Bosch plugs. It's approaching about 84k miles now, although the milage has dropped some 2-3 miles per gallon, where it used to return 29 mpg average on the highway, it's down to 26-27. I'm thinking the 02 sensors are tiring, but there's 4 of them at a Franklin each...yikes! Guess I better be saving for the 100k tune job, let's see, brakes, serpentine belts, fuel filter, trans fluid change ($112 just for the fluid), diff change (also arm and a leg type fluid), inspection 2, and the 02 sensors...
Good luck with the iridiums in the E46 Bill, I know you gave them good reviews when they first came out a few years ago, but I haven't heard a whole lot about them since.
Jr