If you replaced the coils and it's still missing.. I had the same thing happen and tracked it down to the number 1 coil( I pulled the #1 coil off and the car ran the same.... I switch that coil with the a replacment and got the same result. So here's the bad part... When the coil went bad it smoked the DME for the #1 Cylinder. I had to replace the DME to fix... about $800 after searching the internet for a replacment.. Hope to heck it's not the DME... For good measure after replacing the DME ... I replaced all other coils for good measure.... If you see carmel on the coil stop now... Do not risk running or you could smoke the DME.....